One Simple NociScan = Volumes of Personalized Biomarker Data
Backed by Clinical Evidence
Based on methods validated by clinical studies, Aclarion’s proprietary signal processing software and expert system transforms raw spectral MRS data into clear metabolic biomarkers to help physicians determine between painful and nonpainful discs of the lumbar spine.
How it Works
In a conventional MRI, a simple, non-invasive MRS scan gathers raw spectral data on the chemical composition of the lumbar discs.
This raw data is sent to the Aclarion cloud where based on methods validated by clinical studies,1
Aclarion’s proprietary signal processing software and expert system clarifies the signal and transforms the raw data into clear metabolic biomarkers for each disc.
METABOLIC BIOMARKERS
Acidic pain markers 2
Alanine (LAAL = lactic acid + alanine)
Lactic Acid (LAC)
Propionate (PRO)
Structural integrity markers 2
Carbohydrate/collagen (CARB)
Proteoglycan (PG)
Where’s the Pain?
METABOLIC BIOMARKERS
Acidic pain markers 2
Alanine (LAAL = lactic acid + alanine)
Lactic Acid (LAC)
Propionate (PRO)
Structural integrity markers 2
Carbohydrate/collagen (CARB)
Proteoglycan (PG)
Where's the Pain?
Using augmented intelligence in a proprietary, post-processing algorithm, the Aclarion solution analyzes and quantifies the biomarker data, generating ratio metrics for each lumbar disc that are individualized to a normative data set.
NociscoreTM – Pain Biomarker Ratios - measures six biomarker ratios associated with pain generation for each disc
SI-ScoreTM – Disc Structural Integrity Range - measures an MRS range corresponding to the structural integrity biomarker Proteoglycan
Resulting in a simple, streamlined report that efficiently communicates individualized biomarker data for physician interpretation….
Resulting in a simple, streamlined report that efficiently communicates individualized biomarker data for physician interpretation….
NociscoreTM – Pain Biomarker Ratios - measures six biomarker ratios associated with pain generation for each disc
SI-ScoreTM – Disc Structural Integrity Range - measures an MRS range corresponding to the structural integrity biomarker Proteoglycan
So physicians can make critical care decisions, in conjunction with standard practice, about the source of a patient's CLBP and the associated treatment strategy
So physicians can make critical care decisions, in conjunction with standard practice, about the source of a patient's CLBP and the associated treatment strategy
REFERENCES
- 1 Ravindra VM, Global Spine Journal (2018) 8(8): 784-794
- 2 Keshari KR, Spine (2008) 33(3): 312-317
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Aclarion
8181 Arista Place,
Suite 100
Broomfield, CO 80021